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Trilaciclib

CAT: 0931-T13202L-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T13202L-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1374743-00-6
Target
Cell Cycle Arrest, CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
0.99624
Bioactivity
Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC50 values of 1 nM and 4 nM respectively. It transiently and reversibly induces G1 cell cycle arrest, mitigates chemotherapy-induced myelosuppression, and enhances antitumour immunity, making it applicable across multiple cancers.
Smiles
CN1CCN(CC1)c1ccc(Nc2ncc3cc4C(=O)NCC5(CCCCC5)n4c3n2)nc1
Molecular Formula
C24H30N8O
Molecular Weight
446.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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