Sunitinib-d10

• Target:

  PDGFR|||Autophagy|||Mitophagy|||IRE1|||Apoptosis|||VEGFR

• Related Pathways:

  Autophagy|||Angiogenesis|||Apoptosis|||Tyrosine Kinase/Adaptors|||Cell Cycle/Checkpoint

• Bioactivity:

  Sunitinib D10 is a deuterium labeled Sunitinib. Sunitinib is a inhibitor of multi-targeted receptor tyrosine kinase (IC50s of 80 nM and 2 nM for VEGFR2 and PDGFR?, respectively) .

• Smiles:

  [2H]C([2H])([2H])C([2H])([2H])N(CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C)C([2H])([2H])C([2H])([2H])[2H]

• Molecular Formula:

  C22H27FN4O2

• Molecular Weight:

  408.54

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1126721-82-1