Sunitinib

• Target:

  VEGFR|||Apoptosis|||FLT|||Autophagy|||Mitophagy|||IRE1|||PDGFR|||c-Kit

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Angiogenesis|||Apoptosis|||Autophagy|||Cell Cycle/Checkpoint

• Purity:

  0.9967

• Bioactivity:

  Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase (RTK) inhibitor that inhibits VEGFR2 and PDGFR? (IC50=80/2 nM) . It exhibits antitumor activity and is used for treating kidney cancer and gastrointestinal tumors.

• Smiles:

  C(=C\1/C=2C(NC1=O)=CC=C(F)C2)\C3=C(C)C(C(NCCN(CC)CC)=O)=C(C)N3

• Molecular Formula:

  C22H27FN4O2

• Molecular Weight:

  398.47

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  557795-19-4