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Succinyl phosphonate

CAT: 0931-T13020Size: 1 mgDry Ice: NoHazardous: No
T130201 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
26647-82-5
Target
Reactive Oxygen Species|||ROS|||Endogenous Metabolite
Related Pathways
Immunology/Inflammation|||NF-?B|||Metabolism
Bioactivity
Succinyl phosphonate is a selective ?-ketoglutarate dehydrogenase (?-KGDHC) and OGDHC inhibitor that inhibits ?-ketoglutarate oxidative decarboxylation. Succinyl phosphonate trisodium salt inhibits glutamate-induced ROS generation in glutamate-stimulated hippocampal neurons and can be used to study neurodegenerative diseases.
Smiles
O=C(O)CCC(=O)P(=O)(O)O
Molecular Formula
C4H7O6P
Molecular Weight
182.07
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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