Succinyl phosphonate

• Target :

  Reactive Oxygen Species|||ROS|||Endogenous Metabolite

• Related Pathways :

  Immunology/Inflammation|||NF-?B|||Metabolism

• Bioactivity :

  Succinyl phosphonate is a selective ?-ketoglutarate dehydrogenase (?-KGDHC) and OGDHC inhibitor that inhibits ?-ketoglutarate oxidative decarboxylation. Succinyl phosphonate trisodium salt inhibits glutamate-induced ROS generation in glutamate-stimulated hippocampal neurons and can be used to study neurodegenerative diseases.

• Smiles :

  O=C(O)CCC(=O)P(=O)(O)O

• Molecular Formula :

  C4H7O6P

• Molecular Weight :

  182.07

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  26647-82-5