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STL127705

CAT: 0931-T13017-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T13017-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1326852-06-5
Target
Apoptosis, DNA-PK
Related Pathways
DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling, Apoptosis
Purity
0.9981
Bioactivity
STL127705 (Compound L) is a potent inhibitor of the Ku 70/80 heterodimer protein, disrupting Ku70/80-DNA interaction with an IC50 of 3.5 μM, and inhibiting Ku-dependent DNA-PKCS kinase activation with an IC50 of 2.5 μM.
Smiles
COc1ccc(CCNc2ncc3c(n2)[nH]c(=O)n(-c2cccc(F)c2)c3=O)cc1OC
Molecular Formula
C22H20FN5O4
Molecular Weight
437.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BA2757-10STL127705
A18410-10STL127705 10mg
A18410-50STL127705 50mg
A18410-25STL127705 25mg
A18410-500STL127705 500mg
A18410-100STL127705 100mg
A18410-5STL127705 5mg
A18410-1STL127705 1mg
A18410-10mM-DSTL127705 10mM * 1mL in DMSO

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