Alkynyl Palmitic Acid

• Description :

  Alkynyl Palmitic Acid (Alk-C16) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Alkynyl Palmitic Acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Product Name Alternative :

  Alk-C16

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  PROTAC Linkers

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/alkynyl-palmitic-acid.html

• Purity :

  97.0

• Solubility :

  DMSO : 100 mg/mL (ultrasonic) |Ethanol : 50 mg/mL (ultrasonic)

• Smiles :

  C#CCCCCCCCCCCCCCC(O)=O

• Molecular Formula :

  C16H28O2

• Molecular Weight :

  252.39

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Alkyl-Chain Linkers

• CAS Number :

  [99208-90-9]