Rapamycin-d3

• Target:

  FKBP|||Autophagy|||mTOR

• Related Pathways:

  Immunology/Inflammation|||Apoptosis|||PI3K/Akt/mTOR signaling|||Autophagy

• Bioactivity:

  Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific inhibitor of mTOR (IC50 of 0.1 nM in HEK293 cells) .

• Smiles:

  [2H]C([2H])([2H])O[C@H]1C[C@@H]2CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@@H](CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C1/C)[C@H](C)C[C@@H]1CC[C@@H](O)[C@@H](C1)OC

• Molecular Formula:

  C51H79NO13

• Molecular Weight:

  917.19

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  392711-19-2