β-Boswellic acid

CAT: 0804-HY-N2513-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N2513-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
β-Boswellic acid is isolated from the gum resin of Boswellia serrata with anticancer, antioxidant activity, anti-inflammatory activity and anti-arthritic pain.β-Boswellic acid is an orally active nonreducing-type inhibitor of the 5-lipoxygenase (5-LO) product formation either interacting directly with the 5-LO or blocking its translocation. β-Boswellic acid inhibits the synthesis of DNA, RNA and protein in human leukemia HL-60 cells with IC50 values ranging from 0.6 to 7.1 μM. β-Boswellic acid is promising for research of diabetes, inflammatory and arthritic diseases[1][2][3][4].
CAS Number
[631-69-6]
UNSPSC
12352211
Hazard Statement
H302
Target
DNA/RNA Synthesis; Lipoxygenase
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/beta-boswellic-acid.html
Purity
99.89
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@]12[C@@](CC=C3[C@]2(CC[C@]4(C)[C@@]3([H])[C@H]([C@H](C)CC4)C)C)([H])[C@@]5([C@@]([C@](C)([C@H](O)CC5)C(O)=O)([H])CC1)C
Molecular Formula
C30H48O3
Molecular Weight
456.70
Precautions
H302
References & Citations
[1]Safayhi H, et al. Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase. J Pharmacol Exp Ther. 1992 Jun;261 (3) :1143-6.|[2]Shao Y, et al. Inhibitory activity of boswellic acids from Boswellia serrata against human leukemia HL-60 cellsin culture. Planta Med. 1998 May;64 (4) :328-31|[3]Huang MT, et al. Anti-tumor and anti-carcinogenic activities of triterpenoid, beta-boswellic acid. Biofactors. 2000;13 (1-4) :225-30.|[4]Khan A, et al. Anti-diabetic potential of β-boswellic acid and 11-keto-β-boswellic acid: Mechanistic insights from computational and biochemical approaches. Biomed Pharmacother. 2022 Mar;147:112669.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
5-LOX

Related Products

CatalogName
HY-140113-01Acid-PEG3-SS-PEG3-acid
HY-140112-01Acid-PEG2-SS-PEG2-acid
HY-140589Acid-PEG4-S-PEG4-acid
HY-W096114-01Acid-PEG8-S-S-PEG8-acid
HY-140114-01Acid-PEG4-S-S-PEG4-acid
HY-N3860Erythrocentauric acid
HY-120838-01Heptelidic acid
HY-126867Neohydroxyaspergillic acid
HY-N7700Guluronic acid
HY-166261Colnelenic acid

Alternative Products

CatalogName
004549α-Boswellic Acid
AB0461β-Boswellic acid
TRC-B676490-100MGa-Boswellic Acid
591796Boswellic acid
MBS3841085-01alpha-Boswellic acid
TRC-B676500-2.5MGb-Boswellic Acid
MBS5759847Beta-boswellic acid
C4123-10β-acetyl-Boswellic Acid
BUP02704-01SS-Boswellic acid

Popular Products