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CLIC1 rabbit pAb

CAT: 0855-ES20785-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES20785-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Chloride intracellular channel 1 (CLIC1) Homo sapiens Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. [provided by RefSeq, Jul 2008]
Description
Chloride intracellular channel 1 (CLIC1) Homo sapiens Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane Chloride ion channel activity. [provided by RefSeq, Jul 2008],
UniProt
O00299
Swiss Prot
O00299
Reactivity
Human; Rat; Mouse
Immunogen
Synthetic Peptide of CLIC1 AA range: 166-216
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF
Concentration
1 mg/ml
Dilution
IHC 1:100-200
Molecular Weight
30kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
30kD
Fragment
IgG
Subcellular Location
Nucleus . Nucleus membrane ; Single-pass membrane protein . Cytoplasm . Cell membrane ; Single-pass membrane protein . Mostly in the nucleus including in the nuclear membrane (PubMed:9139710, PubMed:12681486) . Small amount in the cytoplasm and the plasma membrane (PubMed:9139710) . Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (PubMed:11940526, PubMed:11551966, PubMed:14613939) . .
Other Product Names
Chloride intracellular channel protein 1 (Chloride channel ABP; Nuclear chloride ion channel 27; NCC27; Regulatory nuclear chloride ion channel protein; hRNCC)
Gene ID (Human)
1192

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