CLIC1 rabbit pAb

CLIC1 rabbit pAb

• Description: Chloride intracellular channel 1 (CLIC1) Homo sapiens Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane Chloride ion channel activity. [provided by RefSeq, Jul 2008],
• Synonyms: Chloride intracellular channel protein 1 (Chloride channel ABP;Nuclear chloride ion channel 27;NCC27;Regulatory nuclear chloride ion channel protein;hRNCC)
• Gene ID: 1192
• UniProt: O00299
• Cellular Locus: Nucleus. Nucleus membrane ; Single-pass membrane protein. Cytoplasm. Cell membrane ; Single-pass membrane protein. Mostly in the nucleus including in the nuclear membrane (PubMed:9139710, PubMed:12681486). Small amount in the cytoplasm and the plasma membrane (PubMed:9139710). Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (PubMed:11940526, PubMed:11551966, PubMed:14613939)..
• Host: Rabbit
• Species Reactivity: Human, Rat, Mouse
• Immunogen: Synthetic Peptide of CLIC1 AA range: 166-216
• Clonality: Polyclonal
• Validated Applications: IHC, IF
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: IHC 1:100-200
• Molecular Weight: 30kD
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.