Pyrotinib dimaleate

• Target:

  HER|||EGFR

• Related Pathways:

  JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis

• Purity:

  0.9952

• Bioactivity:

  Pyrotinib dimaleate is a selective EGFR/HER2 dual inhibitor with IC50 values ??of 13 and 38 nM, respectively, for the treatment of HER2-positive breast cancer.

• Smiles:

  OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\[C@H]1CCCN1C

• Molecular Formula:

  C40H39ClN6O11

• Molecular Weight:

  815.22

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1397922-61-0