Pyrotinib dimaleate

CAT: 0931-T12594-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T12594-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1397922-61-0
Target
HER|||EGFR
Related Pathways
JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis
Purity
0.9952
Bioactivity
Pyrotinib dimaleate is a selective EGFR/HER2 dual inhibitor with IC50 values ??of 13 and 38 nM, respectively, for the treatment of HER2-positive breast cancer.
Smiles
OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\[C@H]1CCCN1C
Molecular Formula
C40H39ClN6O11
Molecular Weight
815.22
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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