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Plecanatide acetate

CAT: 0931-T12501-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T12501-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1075732-84-1
Target
Others, Guanylate cyclase
Related Pathways
Others, GPCR/G Protein
Bioactivity
Plecanatide acetate is a agonist of guanylate cyclase-C (GC-C) receptor (EC50 of 190 nM in T84 cells), and shows anti-inflammatory activity in models of murine colitis.
Smiles
CC(O)=O.[H][C@@]1(CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@]([H])(CSSC[C@]2([H])NC(=O)[C@H](C)NC(=O)C(NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@]([H])(CSSC[C@H](NC(=O)CNC(=O)[C@@]([H])(NC2=O)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(O)=O)NC1=O)C(C)C)C(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CC(N)=O |@:93|
Molecular Formula
C67H108N18O28S4
Molecular Weight
1741.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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A21393-100Plecanatide acetate 100mg
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