Macitentan-d4

• Target:

  Endothelin Receptor|||Apoptosis

• Related Pathways:

  GPCR/G Protein|||Apoptosis

• Purity:

  0.9651

• Bioactivity:

  Macitentan-d4 (ACT-064992 D4) is a deuterated substitute for Macitentan and can be used as a dual antagonist of the non-peptides ETA and ETB (endothelin receptor) .Macitentan-d4 is less toxic than Macitentan, has a longer half-life, and can be used to study endothelin receptor-mediated diseases.

• Smiles:

  N(S(NCCC)(=O)=O)C=1C(=C(OC(C(OC=2N=CC(Br)=CN2)([2H])[2H])([2H])[2H])N=CN1)C3=CC=C(Br)C=C3

• Molecular Formula:

  C19H20Br2N6O4S

• Molecular Weight:

  592.3

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1258428-05-5