Itacitinib adipate

• Target:

  JAK|||Phosphatase

• Related Pathways:

  Stem Cells|||JAK/STAT signaling|||Metabolism|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors|||Angiogenesis

• Bioactivity:

  Itacitinib adipate is an orally bioavailable and selective JAK1 inhibitor, tested for efficacy and safety in a phase II trial in myelofibrosis.

• Smiles:

  N#CCC1(N2N=CC(=C2)C=3N=CN=C4NC=CC43)CN(C1)C5CCN(C(=O)C=6C=CN=C(C6F)C(F)(F)F)CC5.O=C(O)CCCCC(=O)O

• Molecular Formula:

  C32H33F4N9O5

• Molecular Weight:

  699.66

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1334302-63-4