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IFSP1

CAT: 0931-T11631-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T11631-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
150651-39-1
Target
Ferroptosis
Related Pathways
Apoptosis
Purity
0.9974
Bioactivity
IFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse human cancer cell lines to ferroptosis inducers like (1S,3R) -RSL3. It uniquely triggers ferroptosis in GPX4-knockout cells overexpressing FSP1.
Smiles
Cc1ccc(cc1)-c1c(C#N)c(N)n2c3ccccc3nc2c1C#N
Molecular Formula
C20H13N5
Molecular Weight
323.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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B2676-5iFSP1
A22277-10IFSP1 10mg
A22277-5IFSP1 5mg
A22277-25IFSP1 25mg

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