IFSP1

• Target :

  Ferroptosis

• Related Pathways :

  Apoptosis

• Purity :

  0.9974

• Bioactivity :

  IFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse human cancer cell lines to ferroptosis inducers like (1S,3R) -RSL3. It uniquely triggers ferroptosis in GPX4-knockout cells overexpressing FSP1.

• Smiles :

  Cc1ccc(cc1)-c1c(C#N)c(N)n2c3ccccc3nc2c1C#N

• Molecular Formula :

  C20H13N5

• Molecular Weight :

  323.35

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  150651-39-1