HPN-01

• Target:

  I?B/IKK

• Related Pathways:

  NF-?B

• Purity:

  0.9817

• Bioactivity:

  HPN-01 (IKK inhibitor XII) is a selective IKK inhibitor that inhibits IKK-?, IKK-?, and IKK-?. HPN-01 reduces the severity of the disease, attenuates the immune imbalance, and prolongs the lifespan of mice in a model of autoimmune encephalomyelitis, and can be used to study immune disorders.

• Smiles:

  NC(=O)c1cc(cc(c1N)-c1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1

• Molecular Formula:

  C19H16ClN3O3S

• Molecular Weight:

  401.87

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  928655-63-4