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HMG499

CAT: 0931-T11572-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T11572-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2416941-68-7
Target
Autophagy, HMG-CoA Reductase
Related Pathways
Autophagy, Metabolism
Bioactivity
HMG499 is a potent and selective HMG-CoA reductase inhibitor with an IC50 of 0.41 μM, capable of eliminating statins-induced accumulation of HMGCR, lowering serum cholesterol levels, and decreasing atherosclerosis [1].
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C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(CC=C)(CC=C)O)C)(CC4)[H])[H])([C@@H](O)C=C1C(C)(C)[C@@H](O)CC2)[H])[H]
Molecular Formula
C33H54O3
Molecular Weight
498.78
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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