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Garcinol

CAT: 0931-T11366-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T11366-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
78824-30-3
Target
AChR, Cholinesterase (ChE), Apoptosis, Endogenous Metabolite, Histone Acetyltransferase
Related Pathways
Chromatin/Epigenetic, Metabolism, Apoptosis, Neuroscience
Purity
0.9859
Bioactivity
Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM) . Garcinol has anti-inflammatory and anti-cancer activity. Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively.
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CC(C)=CC[C@@H](C[C@@]12C[C@@H](CC=C(C)C)C(C)(C)[C@@](CC=C(C)C)(C(=O)C(C(=O)c3ccc(O)c(O)c3)=C1O)C2=O)C(C)=C
Molecular Formula
C38H50O6
Molecular Weight
602.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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