Garcinol

• CAS Number :

  78824-30-3

• Target :

  AChR|||Cholinesterase (ChE) |||Apoptosis|||Endogenous Metabolite|||Histone Acetyltransferase

• Related Pathways :

  Chromatin/Epigenetic|||Metabolism|||Apoptosis|||Neuroscience

• Purity :

  0.9859

• Bioactivity :

  Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 ?M) and p300/CPB-associated factor (PCAF, IC50 = 5 ?M) . Garcinol has anti-inflammatory and anti-cancer activity. Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 ?M and 7.39 ?M, respectively.

• Smiles :

  CC(C)=CC[C@@H](C[C@@]12C[C@@H](CC=C(C)C)C(C)(C)[C@@](CC=C(C)C)(C(=O)C(C(=O)c3ccc(O)c(O)c3)=C1O)C2=O)C(C)=C

• Molecular Formula :

  C38H50O6

• Molecular Weight :

  602.8

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C