Products for Research Use Only
RegisterLogin

Ganodermanontriol

CAT: 0931-T11365-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T11365-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
106518-63-2
Target
Others, CDK, Wnt/beta-catenin
Related Pathways
Cell Cycle/Checkpoint, Stem Cells, Others, Cytoskeletal Signaling
Purity
0.9997
Bioactivity
Ganodermanontriol is a purified triterpene extracted from GL that inhibits proliferation of HCT-116 and HT-29 colon cancer cells without significantly compromising cell viability and suppresses β-catenin transcriptional activity and cyclin D1 protein levels in a dose-dependent manner. Ganodermanontriol also reduces Cdk-4 and PCNA while increasing E-cadherin and β-catenin accumulation in HT-29 cells, Ganodermanontriol markedly suppresses tumor growth in an HT-29 xenograft mouse model without adverse effects, highlighting its strong potential as a chemotherapeutic candidate for colorectal cancer research.
Smiles
C[C@@]12C=3C([C@@]4(C)[C@](C)(CC3)[C@@]([C@@H](CC[C@@H]([C@](CO)(C)O)O)C)(CC4)[H])=CC[C@]1(C(C)(C)C(=O)CC2)[H]
Molecular Formula
C30H48O4
Molecular Weight
472.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
TN1670-01Ganodermanondiol

Alternative Products

CatalogName
HY-N1506-01Ganodermanontriol
A24403-5Ganodermanontriol 5mg
A24403-10Ganodermanontriol 10mg
A24403-1Ganodermanontriol 1mg
A24403-50Ganodermanontriol 50mg
HY-N1506RGanodermanontriol (Standard)

Popular Products