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Lerociclib

CAT: 0931-T11345-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T11345-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1628256-23-4
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
0.99
Bioactivity
Lerociclib (G1T38) is a selective and highly potent CDK4/6 inhibitor with anticancer and antitumor activity, inhibits CDK4/CyclinD1 and CDK6/CyclinD3, and inhibits tumor growth in an animal model of endocrine-resistant breast cancer. Due to the poor solubility, for animal studies, the salt form T11345L is recommended.
Smiles
O=C1NCC2(N3C=4N=C(N=CC4C=C13)NC5=NC=C(C=C5)N6CCN(CC6)C(C)C)CCCCC2
Molecular Formula
C26H34N8O
Molecular Weight
474.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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