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FG 7142

CAT: 0931-T11277-01Size: 2 mgDry Ice: NoHazardous: No
CAT#:0931-T11277-01Size:2 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
78538-74-6
Target
GABA Receptor
Related Pathways
Neuroscience|||Membrane transporter/Ion channel
Purity
0.9881
Bioactivity
FG 7142 (LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the ?1 subunit (EC50= 137 nM) . FG 7142 can increase tyrosine hydroxylation and cause upregulation of ?-adrenoceptors in mouse cerebral cortex. FG 7142 , a non-selectively benzodiazepine inverse agonist, has high affinity for the ?1 subunit-containing GABAA receptor (Ki=91 nM) .
Smiles
CNC(=O)c1cc2c(cn1)[nH]c1ccccc21
Molecular Formula
C13H11N3O
Molecular Weight
225.25
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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