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Epertinib hydrochloride

CAT: 0931-T11213-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T11213-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2071195-74-7
Target
EGFR, HER
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Purity
0.9936
Bioactivity
Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity. Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively.
Smiles
Cl.CC#C\C(=N/OC[C@H]1COCCN1)c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1
Molecular Formula
C30H28Cl2FN5O3
Molecular Weight
596.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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