EIF4A3-IN-1

• Target:

  PERK

• Related Pathways:

  Apoptosis

• Purity:

  0.9989

• Bioactivity:

  EIF4A3-IN-1 is a selective and potent inhibitor of eukaryotic initiation factor 4A3 (eIF4A3) with an IC50 value of 0.26 ?M. eIF4A3-IN-1 inhibits cytosolic nonsense-mediated RNA decay at high concentrations.

• Smiles:

  C(=O)(N1[C@H](CN(C(=O)C2=C(C)N(N=C2)C3=CC(C#N)=CC=C3)CC1)C4=CC=C(Cl)C=C4)C5=CC=C(Br)C=C5

• Molecular Formula:

  C29H23BrClN5O2

• Molecular Weight:

  588.88

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2095486-67-0