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DC44SMe

CAT: 0931-T10975Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T10975Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1354787-76-0
Target
ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
The IC50 of DC44SMe for Ramos, Namalwa and HL60 / s cancer cells was 2.0 nM, 2.8 nM and 1.9 nM, respectively. DC44SMe can be used for targeted treatment of cancer. DC44SMe is a phosphate prodrug of DC44 and can be used in the synthesis of antibody-drug conjugates (ADC) .
Smiles
C(=O)(N1C2=C(C=3C(C(OP(=O)(O)O)=C2)=CC=CC3)[C@H](CCl)C1)C=4NC=5C(C4)=CC(NC(=O)C=6NC=7C(C6)=CC(NC(CCC(SSC)(C)C)=O)=CC7)=CC5
Molecular Formula
C38H37ClN5O7PS2
Molecular Weight
806.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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