DC0-NH2

• Target:

  ADC Cytotoxin

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Bioactivity:

  The cytotoxicity of DC0-NH2 is 1000 times that of commonly used anti-cancer drugs (such as doxorubicin) . It is the effect part of ADC. It is a simplified simulation of DC1 and has better stability. DC0-NH2 can bind to the small groove of DNA, and then adenine residue is alkylated by its propabenzindole (CBI) component.

• Smiles:

  Nc1ccc2[nH]c(cc2c1)C(=O)Nc1ccc2[nH]c(cc2c1)C(=O)N1C[C@@H](CCl)c2c1cc(O)c1ccccc21

• Molecular Formula:

  C31H24ClN5O3

• Molecular Weight:

  550.01

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  615538-51-7