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Zolmitriptan

CAT: 0931-T1092-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T1092-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
139264-17-8
Target
Endogenous Metabolite, 5-HT Receptor
Related Pathways
Metabolism, GPCR/G Protein, Neuroscience
Purity
0.9991
Bioactivity
Zolmitriptan (311C90) selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries and 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and central terminals in brainstem sensory nuclei. Zolmitriptan is a member of the triptan class of agents with anti-migraine properties. Receptor binding results in constriction of cranial vessels, reduction of vessel pulsation and inhibition of nociceptive transmission, thereby providing relief of migraine headaches. Zolmitriptan may also relieve migraine headaches by inhibition of pro-inflammatory neuropeptide release.
Smiles
C(CN(C)C)C=1C=2C(NC1)=CC=C(C[C@@H]3NC(=O)OC3)C2
Molecular Formula
C16H21N3O2
Molecular Weight
287.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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