CRA-026440

• Target :

  Apoptosis|||HDAC

• Related Pathways :

  Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Apoptosis

• Purity :

  0.9642

• Bioactivity :

  CRA-026440 (PCI-34051) is a highly potent HDAC inhibitor with inhibitory effects on HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki values of 4,14,11,15,7 and 20 nM, respectively. CRA-026440 has anti-tumor and anti-angiogenic activity and can be used to study colon cancer.

• Smiles :

  O=C(NO)C1=CC=C(C#CCNC(=O)C2=CC=3C=C(OCCN(C)C)C=CC3N2)C=C1

• Molecular Formula :

  C23H24N4O4

• Molecular Weight :

  420.46

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  847460-34-8