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BRAF V600E/CRAF-IN-2

CAT: 0931-T63882-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63882-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2499499-62-4
Target
Others, Raf
Related Pathways
Others, MAPK
Bioactivity
BRAF V600E/CRAF-IN-2 is a potent inhibitor of BRAFV600E/CRAF with IC50 values of 0.888 and 0.229 μM, respectively.BRAF V600E/CRAF-IN-2 induces cell cycle arrest at G0/G1 phase and apoptosis in HCT-116 colon cancer cells.BRAF V600E/CRAF-IN-2 has shown research potential for cancer disease. CRAF-IN-2 has shown potential for research into cancer disease.
Smiles
C(NC1=CC(NC2=NC3=C(C=C2)C(OC)=CC=C3)=CC=C1)(=O)C=4C=C(C=C(C(F)(F)F)C4)N5CCN(CC)CC5
Molecular Formula
C30H30F3N5O2
Molecular Weight
549.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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