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Ceranib-2

CAT: 0931-T10761-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T10761-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1402830-75-4
Target
Apoptosis, LPL Receptor, S1P Receptor
Related Pathways
GPCR/G Protein, Apoptosis
Purity
0.9849
Bioactivity
Ceranib-2 (3-[ (E) -3- (4-hydroxyphenyl) prop-2-enoyl]-4-phenyl-1H-quinolin-2-one) is an inhibitor of ceramidase with an IC50 of 28 μM in SKOV3 cells. Ceranib-2 decreases levels of sphingosine and S1P, induces cell apoptosis and exhibits anticancer activity.
Smiles
COc1ccc(\C=C\C(=O)c2c(-c3ccccc3)c3ccccc3[nH]c2=O)cc1
Molecular Formula
C25H19NO3
Molecular Weight
381.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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