BI-4020

CAT: 0931-T10534-01Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T10534-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

2664214-60-0

Target

EGFR

Related Pathways

JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis

Purity

>99.99%

Bioactivity

BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase. It exhibits activity against the triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM in BaF3 cell lines), the double mutant EGFR del19 T790M and primary mutant EGFR del19 (IC50=1 nM), and EGFR wt (IC50=190 nM) . BI-4020 also shows high kinome selectivity and good DMPK properties.

Smiles

C[C@@H]1CCCOc2c(cnn2C)-c2cc(cc(C)n2)C(=O)\N=C2/Nc3ccc(CN4CCN(C)CC4)cc3N2C1

Molecular Formula

C30H38N8O2

Molecular Weight

542.68

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Related Products

Catalog	Name
T9901A-951-01	BI-1206
T9901A-1688-01	BI-655064
T85354-01	BI-4732
T208809-01	BI 1265162
T206466-01	BI-1915
T12979-01	BI-3406
T36478	BI-6901
T79313-01	BI 7446
T73332-01	BI-685509
T14664-01	BI 689648

Alternative Products

Catalog	Name
GTR19178357-01	BI-4020
A22046-100	BI-4020 100mg
A22046-25	BI-4020 25mg
A22046-10	BI-4020 10mg
A22046-200	BI-4020 200mg
A22046-50	BI-4020 50mg
A22046-1	BI-4020 1mg
A22046-5	BI-4020 5mg
A22046-10mM-D	BI-4020 10mM * 1mL in DMSO
B2798-500	BI

BI-4020

Related Products

Alternative Products

Popular Products