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Beclomethasone 17-propionate

CAT: 0931-T10494-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T10494-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
5534-18-9
Target
Drug Metabolite, Glucocorticoid Receptor
Related Pathways
Endocrinology/Hormones, Metabolism
Purity
0.9806
Bioactivity
Beclomethasone 17-propionate is a glucocorticoid that is the active metabolite of Beclomethasone dipropionate (BDP) . As a glucocorticoid receptor (GR) agonist, 17-BMP has a 13-fold higher affinity than BDP and inhibits the production of pro-inflammatory cytokines, such as CXCL8, TNF-α, and IL-6, thus exerting an anti-inflammatory effect, and it is mainly used in the treatment of asthma and allergic rhinitis.
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O(C(CC)=O)[C@@]1(C(CO)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](Cl)([C@@H](O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H]
Molecular Formula
C25H33ClO6
Molecular Weight
464.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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