AR-A 2

• Target:

  Others|||5-HT Receptor

• Related Pathways:

  GPCR/G Protein|||Neuroscience|||Others

• Bioactivity:

  AR-A 2 is a selective 5-HT1B receptor antagonist with high affinity to guinea pig cortex 5-HT1B/1D and recombinant guinea pig 5-HT1B receptors (Ki: 0.24 and 0.47 nM), exhibiting a 10-fold lower affinity to guinea pig 5-HT1D receptor (Ki: 5 nM) .

• Smiles:

  CC1=C2C(=C(C=C1)N3CCN(C)CC3)C[C@H](NC(=O)C4=CC=C(C=C4)N5CCOCC5)CC2

• Molecular Formula:

  C27H36N4O2

• Molecular Weight:

  448.6

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  220051-79-6