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A-9758

CAT: 0931-T10210-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T10210-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2055271-22-0
Target
ROR|||Interleukin
Related Pathways
Metabolism|||Immunology/Inflammation
Bioactivity
A-9758 is a ROR? ligand and selective ROR?t inverse agonist (IC50: 5 nM) that effectively suppresses IL-17A release, Th17 differentiation, and Th17 effector function, significantly attenuating IL-23 driven psoriasiform dermatitis.
Smiles
CN1C=2C(C=C1CC3=C(Cl)C(C(=O)N4CCC(C(O)=O)CC4)=CC=C3Cl)=C(C)C=C(C(F)(F)F)C2
Molecular Formula
C25H23Cl2F3N2O3
Molecular Weight
527.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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