7-Methylguanine

• Target :

  Endogenous Metabolite|||PARP

• Related Pathways :

  DNA Damage/DNA Repair|||Chromatin/Epigenetic|||Metabolism

• Purity :

  0.9999

• Bioactivity :

  7-Methylguanine is an orally available PARP1 inhibitor (Ki=61 ?M) that competes with the substrate NAD+, exhibiting anticancer activity. As a natural nucleic acid metabolite, it may serve as a probe for protein-DNA interactions.

• Smiles :

  O=C1N=C(N)NC=2N=CN(C12)C

• Molecular Formula :

  C6H7N5O

• Molecular Weight :

  165.15

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  578-76-7