7-Methylguanine

CAT: 0931-T10194-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T10194-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

578-76-7

Target

Endogenous Metabolite, PARP

Related Pathways

DNA Damage/DNA Repair, Chromatin/Epigenetic, Metabolism

Purity

0.9999

Bioactivity

7-Methylguanine is an orally available PARP1 inhibitor (Ki=61 μM) that competes with the substrate NAD+, exhibiting anticancer activity. As a natural nucleic acid metabolite, it may serve as a probe for protein-DNA interactions.

Smiles

O=C1N=C(N)NC=2N=CN(C12)C

Molecular Formula

C6H7N5O

Molecular Weight

165.15

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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