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(5Z,2E) -CU-3

CAT: 0931-T10177-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T10177-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1815598-71-0
Target
Apoptosis
Related Pathways
Apoptosis
Purity
0.9902
Bioactivity
(5Z,2E) -CU-3 is a potent and highly selective inhibitor of the DGKα isozyme with an IC50 value of 0.6 μM, competing with ATP and exhibiting a Km value of 0.48 mM. It specifically targets the catalytic region of DGKα without affecting the regulatory region and has demonstrated antitumor and immunogenic effects by promoting cancer cell apoptosis and T cell activation.
Smiles
O=C1N(NS(=O)(=O)c2ccccc2)C(=S)S\C1=C/C=C/c1ccco1
Molecular Formula
C16H12N2O4S3
Molecular Weight
392.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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