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Acetohexamide

CAT: 0931-T0816-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T0816-01Size:1 mL - 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
968-81-0
Target
NADPH, Potassium Channel, Others
Related Pathways
Metabolism, Membrane transporter/Ion channel, Others
Purity
0.9985
Bioactivity
Acetohexamide (Acetohexamid) is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (KIR6.2) with Ki values of 22.9 and 14.2 μM in HEK293 cells transfected with the human receptor and in rat brain, respectively. Acetohexamide is metabolized in the liver to its active metabolite hydroxyhexamide.
Smiles
CC(=O)c1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1
Molecular Formula
C15H20N2O4S
Molecular Weight
324.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C