Quetiapine

CAT: 0931-MF-0003203-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
CAT#:0931-MF-0003203-01Size:1 mL - 10 mM (in DMSO)
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
111974-69-7
Target
Histamine Receptor|||Dopamine Receptor|||5-HT Receptor|||AChR|||Adrenergic Receptor
Related Pathways
GPCR/G Protein|||Neuroscience|||Immunology/Inflammation
Purity
>99.99%
Bioactivity
Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is thought by mediated through antagonist activity at serotonin and dopamine receptors. Specifically, the D1 and D2 dopamine, the ?1 adrenoreceptor and ?2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also can inhibit the histamine H1 receptor.
Smiles
OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12
Molecular Formula
C21H25N3O2S
Molecular Weight
383.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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