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Aspirin

CAT: 0931-T0005-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0931-T0005-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
50-78-2
Target
COX, Autophagy, Mitophagy, Virus Protease
Related Pathways
Autophagy, Microbiology/Virology, Neuroscience, Immunology/Inflammation
Purity
>99.99%
Bioactivity
Aspirin is an orally active, selective, and irreversible inhibitor of COX-1 and COX-2 with IC50 values of 5 and 210 μg/mL, respectively. It induces apoptosis, inhibits NF-κB activation and platelet prostaglandin synthesis, thereby preventing thrombosis. Additionally, it acts as a histone deacetylase inhibitor that upregulates p21, exhibiting anti-inflammatory, antipyretic, analgesic, and anti-platelet aggregation activities. Aspirin is commonly used to induce gastric ulcer models.
Smiles
CC(=O)OC1=CC=CC=C1C(O)=O
Molecular Formula
C9H8O4
Molecular Weight
180.16
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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