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PQM130

CAT: 0804-HY-128346-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-128346-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PQM130, a Feruloyl-Donepezil Hybrid compound with brain penatration, is a multitarget agent candidate against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity. PQM130 acts as a neuroprotective compound for anti-AD agent development[1].
CAS Number
2089415-51-8
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pqm130.html
Purity
99.17
Solubility
DMSO : 1.82 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(OCC1CCN(CC2=CC=CC=C2)CC1)/C=C/C3=CC=C(O)C(OC)=C3
Molecular Formula
C23H27NO4
Molecular Weight
381.46
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Morroni F, et al. PQM130, a Novel Feruloyl-Donepezil Hybrid Compound, Effectively Ameliorates the Cognitive Impairments and Pathology in a Mouse Model of Alzheimer's Disease. Front Pharmacol. 2019 Jun 12;10:658.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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