Lactose

• Description:

  Lactose is a β-galactoside consisting of galactose and glucose residues, the main carbohydrate in mammalian breast milk. Lactose, a macronutrient and an inducer of host innate immune responses, possesses immune modulatory functions[1][2][3].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Endogenous Metabolite; ERK; Interleukin Related; NF-κB

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/Lactose.html

• Purity:

  98.0

• Solubility:

  DMSO : 50 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

• Smiles:

  OC[C@@H]1[C@H] (O) [C@H] (O) [C@@H] (O) [C@H] (O[C@@H] ([C@H] (O) [C@@H] (O) C=O) [C@H] (O) CO) O1

• Molecular Formula:

  C12H22O11

• Molecular Weight:

  342.30

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Kleessen B, et al. Effects of inulin and lactose on fecal microflora, microbial activity, and bowel habit in elderly constipated persons. Am J Clin Nutr. 1997 May;65 (5) :1397-402.|[2]Pan LL, et al. Lactose Induces Phenotypic and Functional Changes of Neutrophils and Macrophages to Alleviate Acute Pancreatitis in Mice. Front Immunol. 2018 Apr 17;9:751.|[3]Paasela M, et al. Lactose inhibits regulatory T-cell-mediated suppression of effector T-cell interferon-γ and IL-17 production. Br J Nutr. 2014 Dec 14;112 (11) :1819-25.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  Launched

• Isoform:

  Human Endogenous Metabolite

• CAS Number:

  63-42-3