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Recombinant Human ATXN3

CAT: 0710-P2534-01Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0710-P2534-01Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
AT3, ataxin 3, ATX3, ATXN3, JOS, MJD, MJD1, SCA3
UniProt
P54252
Expression Region
1-200
Host
E.Coli
Tag
N-terminal His-IF2DI Tag
Applications
Western Blot, ELISA
Field of Research
Neuroscience, Metabolism, Developmental biology
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Lyophilized powder
Reconstitution
Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/ml by gently pipetting 2-3 times, don't vortex.
Molecular Weight
43.8 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
The lyophilized protein is stable at -20 °C for up to 1 year. For extended storage, it is recommended to further dilute in working aliquots after reconstitution. The protein solution is stable at ≤ -20 °C for 3 months, or 2-7 days at 2-8 °C under sterile conditions.Avoid repeated freeze/thaw cycle.
Formulation
Lyophilized from a 0.2 μm filtered solution of 10 mM Hepes, 150 mM NaCl with 5% trehalose, pH 7.4.
Organism Species
Human

UniProtKB · P54252

Ataxin-3

ATX3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P54252
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ATXN3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.19.12
Processing
—
Secondary accessions
A7LFZ5, D6RDL9, E9PB63, O15284, O15285, O15286, Q8N189, Q96TC3, Q96TC4, Q9H3N0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicingTriplet repeat expansion

Molecular function

HydrolaseProteaseThiol protease

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Cellular component

LysosomeMembraneNucleus

Disease

NeurodegenerationSpinocerebellar ataxia

Domain

Repeat

Biological process

TranscriptionTranscription regulationUbl conjugation pathway

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