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Glyparamide

CAT: 0804-HY-15383-02Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-15383-02Size:10 mM - 1 mL
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Description
Glyparamide is an orally active chlorophenyl-containing sulfonylurea. Glyparamide shows hypoglycemic activity and rarely causes hepatic injury[1].
CAS Number
5581-42-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Glyparamide.html
Purity
98.43
Solubility
DMSO : 55 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C(Cl)C=C1)(NC(NC2=CC=C(N(C)C)C=C2)=O)=O
Molecular Formula
C15H16ClN3O3S
Molecular Weight
353.82
Precautions
H302, H315, H319, H335
References & Citations
[1]Yuntao Liu, et al. Emerging Theranostic Nanomaterials in Diabetes and Its Complications. Adv Sci (Weinh) . 2022 Jan;9 (3) :e2102466.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Glyparamide

Glyparamide is a chlorophenyl-containing sulfonylurea with hypoglycemic activity. Glyparamide rarely causes hepatic injury.

CAS Number5581-42-0
PubChem CID246940
IUPAC Name1-(4-chlorophenyl)sulfonyl-3-[4-(dimethylamino)phenyl]urea
Molecular FormulaC15H16ClN3O3S
Molecular Weight353.8
XLogP3.7
Topological Polar Surface Area86.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count23
Formal Charge0
Complexity491
SMILES
CN(C)C1=CC=C(C=C1)NC(=O)NS(=O)(=O)C2=CC=C(C=C2)Cl
InChI
InChI=1S/C15H16ClN3O3S/c1-19(2)13-7-5-12(6-8-13)17-15(20)18-23(21,22)14-9-3-11(16)4-10-14/h3-10H,1-2H3,(H2,17,18,20)
InChIKey
SUQZXLUIKZXADU-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Glyparamide
CAS: 5581-42-0
CID: 246940
Formula: C15H16ClN3O3S
MW: 353.8
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight353.8
XLogP33.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass353.0600902
Monoisotopic Mass353.0600902
Topological Polar Surface Area86.9 Ų
Heavy Atom Count23
Formal Charge0
Complexity491
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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