ST6GalNAc1, soluble fragment, Human Recombinant

CAT:

26-P1223-5

Size:

5 µg

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Description: Alpha-N-acetylgalactosaminide α-2,6-sialyltransferase 1 catalyzes the transfer of sialic acid N-acetylneuraminic acid (Neu5Ac) from cytidine 5'-monophosphono-N-acetylneuraminic acid (CMP-Neu5Ac) to O-linked GalNAc residues in an α-2,6 linkage. ST6GalNAcI belongs to a large family of Golgi-membrane-bound sialyltransferases that is responsible for the biosynthesis of sialyated structures, and from which approximately 20 have been cloned to date. The cancer associated sialyl-Tn (sTn) angtigen is formed by ST6GalNAcI, through the transfer of Neu5Ac to GalNAc resiudes on mucins. Addition of a sialic acid to a glyco-protein effectively caps the glycan-chain, preventing further additions. The presence of sialic acid residues extends the half-life of circulating proteins, and are considered to be important for a large variety of biotherapuetics.
CAS Number: 9000-83-3
Shipping Conditions: Gel Pack
Storage Conditions: -20°C
Shelf Life: 12 months

Cat	Name
P1223-5	ST6GalNAc1, soluble fragment, Human Recombinant
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