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Active Human Caspases Group I, Active Human

CAT: 0026-K241-3-25Size: 3x 25 Units. Group I contains active caspase-1/-4/-5.Dry Ice: NoHazardous: No
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CAT#:0026-K241-3-25Size:3x 25 Units. Group I contains active caspase-1/-4/-5.
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The caspase family consists of more than 10 members. Based on their extended substrate specificities, these enzymes were divided into three major groups: Group I (contains caspase-1,-4,-5), Group II (contains caspase-2,-3,-7), and Group III (contains caspase-6,-8,-9,-10). Evidences have suggested that Group I caspases are involved primarily in the production of inflammatory cytokines, while group II and III enzymes function in apoptosis as effectors and upstream activators, respectively. The group I caspases were expressed in E. coli and routinely tested for their ability to enzymatically cleave the substrate YVAD-pNA (for caspase-1) and WEHD-pNA (for caspase-4 & -5).
Shipping Conditions
gel pack
Storage Conditions
-70°C
Shelf Life
12 months

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