Mouse Recombinant DHFR

CAT: 0026-6383-100Size: 100 µgDry Ice: NoHazardous: No
CAT#:0026-6383-100Size:100 µg
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Description
Dihydrofolate reductase (DHFR) is a member of the reductase family of enzymes that is ubiquitously expressed in all organisms. DHFR catalyzes the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, and it is essential for the synthesis of thymidylate, purines and several amino acids. Expression of methotrexate (MTX)-resistant variants of DHFR in normal hematopoietic cells is a potential strategy to permit administration of larger doses of MTX by alleviating drug toxicity in normal cells and tissues that are drug sensitive.
CAS Number
9000-83-3
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
12 months

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