Mouse Recombinant DHFR

CAT:

26-6383-100

Size:

100 µg

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Description: Dihydrofolate reductase (DHFR) is a member of the reductase family of enzymes that is ubiquitously expressed in all organisms. DHFR catalyzes the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, and it is essential for the synthesis of thymidylate, purines and several amino acids. Expression of methotrexate (MTX)-resistant variants of DHFR in normal hematopoietic cells is a potential strategy to permit administration of larger doses of MTX by alleviating drug toxicity in normal cells and tissues that are drug sensitive.
CAS Number: 9000-83-3
Shipping Conditions: gel pack
Storage Conditions: -20°C
Shelf Life: 12 months

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