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Human Recombinant Cyclophilin B

CAT: 0026-6310-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0026-6310-100Size:100 µg
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Description
Cyclophilin B is a cyclosporine-binding protein. It is both secreted and retained in the ER. When secreted, Cyclophilin B mediates chemotaxis and T cell adhesion to fibronectin. This is likely due to its prolyl cis/trans isomerase activity. Intracellularly, Cyclophilin B appears to serve as a molecular chaperone for molecules destined for secretion. It does so via stabilization, and facilitating the activity of additional chaperones. It also bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression.
CAS Number
9000-83-3
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
12 months

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