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Caspase-4, human recombinant

CAT: 0026-1084-25Size: 25 UnitsDry Ice: NoHazardous: No
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CAT#:0026-1084-25Size:25 Units
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Caspase-4 (also know as Ich-4, ICErelII, TX) is a member of the caspase-family of cysteine proteases. Similar to other caspases, caspase-4 exists in cells as an inactive proenzyme which is matured by proteolysis to yield large and small subunits. The active caspase-4 is a heterotetramer consisting of two large and two small subunits. To date the mechanism of caspase-4 activation and roles of caspase-4 in apoptosis are poorly understood. The recombinant active human caspase-4 was expressed in E. coli. The active caspase-4 is routinely tested at BioVision for its ability to enzymatically cleave these two substrates Ac-WEHD-pNA (Cat. #1102-200) or Ac-WEHD-AFC (1101-200).
CAS Number
9000-83-3
Shipping Conditions
gel pack
Storage Conditions
-70°C
Shelf Life
12 months