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Caspase-2, human recombinant

CAT: 0026-1082-25Size: 25 UnitsDry Ice: NoHazardous: No
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CAT#:0026-1082-25Size:25 Units
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Caspase-2 (also know as Ich-1, Nedd-2) is a member of the caspase-family of cysteine proteases. Similar to other caspases, caspase-2 also exists in cells as an inactive proenzyme. During apoptosis pro-caspase-2 is processed at aspartate residues by self-proteolysis and/or cleavage by upstream caspases. The processed active caspase-2 is a heterotetramer consisting of two large (19 kDa) and two small (12 kDa) subunits.The recombinant active human caspase-2 was expressed in E. coli. The active caspase-2 preferentially cleaves caspase-2 substrates (e.g., VDVAD-AFC or VDVAD-pNA) and is routinely tested at BioVision for its ability to enzymatically cleave these two substrates Ac-VDVAD-pNA (Cat. #1072-200) or Ac-VDVAD-AFC (1071-200).
CAS Number
9000-83-3
Shipping Conditions
gel pack
Storage Conditions
-70°C
Shelf Life
12 months

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