PF-06840003

CAT: 0026-B2218-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B2218-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-06840003 is a highly selective orally bioavailable indoleamine 2,3-dioxygenase -1 (IDO-1) inhibitor (IC₅₀ = 0.15 μM for human enzyme). It inhibits IDO-1-mediated production of kynurenine induced by IFN-γ in HeLa cells (IC₅₀ = 1.8 µM) and by LPS and IFN-γ in THP-1 cells and human-derived whole blood ex vivo (IC₅₀s = 1.7 and 4.7 µM, respectively).
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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