Sivelestat

CAT: 0026-B2144-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B2144-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sivelestat (ONO-5046) is a potent neutrophil elastase inhibitor. It acts as a substrate-competitive, and highly specific inhibitor of neutrophil elastase (IC₅₀ = 19-49 nM in rat, rabbit, hamster, human, and mouse leukocyte elastase). Sivelestat displays >100-fold greater selectivity over pancreatic elastase (IC₅₀ = 5.6 μM). It does not inhibit trypsin, thrombin, plasmin, kallikrein, chymotrypsin, and cathepsin G even at concentrations as high as 100 μM.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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