BMS-536924

CAT: 0026-B1908-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B1908-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMS-536924 is a dual inhibitor of insulin-like growth factor receptor (IGF-1R) kinase and insulin receptor (IC₅₀s = 100 and 73 nM, respectively). Inhibits receptor autophosphorylation and downstream MEK1/2 and Akt signaling. Induces G1 arrest and apoptosis in ML-1 cells; also inhibits cell proliferation in multiple tumor types. Cell-permeable.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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